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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225d4ad7d8e27430e8c5b5ff56bab573688558a7682febce528f13af58bb6d54' 
  AND token = 'D2IZpB+oXTufl9n+TsadxBlhYLxjyIZC1exWBAvQsQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}