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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e7912369368f6accff64c150f0243c8ebf7b70fdcc4d5a630c0db4354eb8cf' 
  AND token = '6wTM+teHbi2mJAElUeISt3YrmW/zR7wmAPVABhhVDEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}