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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a218e4b3e5ce13ec00ccf440f5fa53ef753ecadb7afd44bf9a52c18d1233a5f3' 
  AND token = 'ikI/HlLokQLd+8gYrvaaoh3zEblBlDjr9MNF/O62mzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}