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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e77efaa2727b57e721a10ecd3eceb5975365b33aabb1643c2f1b075a5223c0' 
  AND token = 'YvXNLgIAcJYaySoC4FDB+8JQO/i7XvId8nF8TqViIg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}