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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18bf49928951a6e8aaeead3b0bb097cdaedc20a23568f0884a7f97df778dd3a9' 
  AND token = 'EgV+WOoRrPoYNiY/1lo3V14gPY3ZiIYLyS3/eBu8aQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}