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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcafe8b8e7ef62f23feaa0e6a95724006ebce8df0e167b375648e81d89d5a6e5' 
  AND token = 'GKxazYb1L6G3sYWwH2+epxHVxRg27u7IaM7rR/WxhGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}