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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b52259086080b7b9474d4f648fa34773361e23b4fc0da1c09a81d2e20a7e952' 
  AND token = 'jEDm7SgidX+WhcDF8SreVOm0X2vQiIQLFwwWvJzA0to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}