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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effea326539a6a25d2668c4821b4c75a5231dee7816396d45d3c0349465b77d6' 
  AND token = 'kskOLFYo/G7PWqh/3aTkF8lcROQ95ejUcNmH/oJnNnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}