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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48006c7eac5bcca5a43c5b789d9bd3966b00a5a941661647eaf1befd5e67a1f3' 
  AND token = 'AdZF5cnBuluwxVI9qqzQ+yDGA2hFa48Xfmz9+Z123MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}