SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18aab3ef9d18b06bb2ccfce621a28d325d406332a2222aad0e229e651ab61db0' 
  AND token = 'nHIas8pqqPx0hxM8qex+A1QsrQx9O5fr2IPTdH4SJ8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}