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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7439e6723f11ffb5ae4ea7e85b347443919b1051723b64d04bfd49ff38d0ac' 
  AND token = 'lQaugJbZ4RpEIOsOL/l0QGYpTOcqKfkwdR6gwOLQyqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}