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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548aedb4e4526faf88747c41e4410e449fbdd1528f69e797c741480dd4db765b' 
  AND token = 'CT/akChp3HH9lSLzTc6NkT7gZt1+x8jIsSt9SwFh2vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}