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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8280a3444c12f98bbfbfe46ed3ca14391e0244522d1b90c3e891759791ed86e0' 
  AND token = 'scZ6uSn/HZf7FZwzX0UPokuEEXdRkAQVz/4V/DtHgQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}