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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72e10d203f5897651009993225d0e4c22e089d630f85630e68c7296260577dd' 
  AND token = 'ZZ3djiYKc9mwM+VGkJD9+xQmNADXrzyHoaU2NfkOH2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}