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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ec8a72a39005cf3b6657eaebb64c3d7e3394fb3a5d886a16d3a3c24daea225' 
  AND token = 'cYMZLcYL/El5tBDZBO1VcNBwmk/3+8SSSvxjXUSM4bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}