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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f224bb5d92e68fd2106272dc41b6f3d3db5ffd5953ad3e104837c2b0e2cb224' 
  AND token = 'BoqpTLv7O1m2RWHRRQ5mjBi7m1LIdQPQEC7AaAEOaHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}