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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ea8e50b4d527a7e1c52d503b44f488cf456e4aeb859d1f0a8a63fd10ab2849' 
  AND token = 'V44dy7pcb/+2ba4ltZYhv44HWG5oPqfSvVuOZqTx05I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}