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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '875c9219529310e33acac245ce31f2c818c1d45f0daeda4ef44bcf6217c3b70b' 
  AND token = 'yEcsyUDd775ngSYU0R5jExvk5TUyy7TyCZA86oL7IOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}