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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2775dd55770f85326c04975c1a9249402a2fef726b7e9ea7c3ddeaabe9b2a6a' 
  AND token = 'S2nYW0DB9zSWVMRrjyMl3WnrS/Nn6CZjE00DYkud2Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}