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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae33b853a70e69e45f3132c7f0c65661f62a267832229e4ba30ccbc17704e88f' 
  AND token = 'w8CSAJ0RX4QVatzYsGe+7aXZmF0SUZ5pvRBoz0weh0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}