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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580d3ede093b082f1ba6396ffef9500bad858729a9d3d3f2107a362ece9b5d00' 
  AND token = 'Y+INGCS+ke4u0x0p1N9OSTKrjS/mJ4OGHHWlEU2Lu3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}