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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22232a647daff329ea94beca567f46c389c49e7e22d38d9fef5f3268252fb4f5' 
  AND token = 'W/6896orzwmcfFzlchDo7PJE0c2NqE1XwhLUuxh2Ttw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}