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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d1e5c0fa30f31158d21d2a56694b9330c6dbf387a35d9216b9c7c997f51a10' 
  AND token = 'd2gMqrfxPlT04iHZkmKsk1QKK5shKNnYt1127tkVcEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}