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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0378b4e8b49c1329082c3747b44f6b47f70e672a19cc22d5bdab31e71d5b8e37' 
  AND token = 'qaeFo1168WrQz8ng+AxkhbBHWtBCEHKZe2+zj1QX9gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}