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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd780333a0cb72d4db8ebc32da9078b9db726fc7d9cf483cb04db447a3e85be' 
  AND token = 'bq/Y3c1UVdGNiHzHByjU3Gg3t2EZiu1mPAzbDyXvDuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}