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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fdb466fe18f7d85cfea65625dd8368d9f1708ae5a2a0019e0e74c22850c2f2' 
  AND token = 'v9cWanpsFTZKbnRRFzFGPtjObgTFTvDcWHd3pASWLqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}