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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95ca3180b6ed506a53f0ea06bce4ee2c4aff807eabcc6e0ab59fd14c233436ab' 
  AND token = 'wIOHCcgjINJ30hf+f+DH3FWXQ4CXsaMjZnYI10Qmpn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}