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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04aca3230559c804a616a605c87e4ab6505ff8a669bc729c2f59417105f23c78' 
  AND token = 'ekqB/fSJiEulpq1ty+GVsnjEGOTD3puoprw2xnk26kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}