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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a3e4b67fd04a49d4dfe6183e6cea1329ca005212cce925e36f3a3af84ddfb9' 
  AND token = 'obn9uShOs2IQQp3qd0vmWWrhHHOGmmH0oAS1i6kVpIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}