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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8493635ea59ddff7a00300bfc0133c59e1b3d48658fb6a1f3b9b8e76cac9416' 
  AND token = 'nSlKoOlNjmCSddmcxWV/Ws7M6a3czYh3gTJIfkW7qHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}