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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b49f5e20fe15def32455e0c38f3b9607ffcacd4a46e337becaedac36a265e2' 
  AND token = 'v1v//QxzXMvyTC6T3FJn8zrVzUHWmxEA+nxYP7p96KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}