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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b59a52aaa10575a7e9400bb391aa5c6085a017d3c046deff5455a76e8d113a' 
  AND token = '5jxzBUJRmOpgbCLDr/4l38fqZZPkwaPtxQicpt+OyUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}