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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b46eaa11be884e80217f15c95c6aa31f101a4a48e615d03c23afb9bf0905607' 
  AND token = 'gpYYqMoJod9XZ8B5bdp3XBlEU9O0ETdC12+G/AUS/Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}