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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '007b897284f73b0fe09d9b1d86b40d69d0d4cb8d4e50825000e0564337588109' 
  AND token = 'ToS5oz++UtLxXqGviEzJNcAgUBsIopKSiiq6phQAv9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}