SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c100c1280fff4c2d400bbd698adedf0d6ad0e34b385a75240ec75698833545c' 
  AND token = '+SXlrVPgp2m8AzDd7Bao8AbwqX+4uuQLp3JsMfc6kts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}