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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781bb7a20f9da17d2827cfbcdae19f486a3c351871a649d85f7398b921ec9741' 
  AND token = 'Xqi6TD0hveI+8FaJ9M8bzki91/jV4orxsPuV2kgHXEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}