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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e7a8c99354b9e152df588ad46cb7e5ee107ab9dcb1978eb12cd9d8b6686f5c' 
  AND token = 'o15WZvWc4CheexPbZ4HzwK9SAnKLuUw5pBmVPq2wsvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}