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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122e1aed521d278f8aec4d1a578b8f6df0dbcb7ff5cc15b42f08933189f85b15' 
  AND token = 'dLpPEKrYLXHFC1daExqMZfXRHkSYw8kSycfFTVxzF5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}