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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8facef9bf582da27bb1281dd49deb16011ff1f7901f98574bc100f7f5b541bc2' 
  AND token = 'LTaZVoMbOChw+WQ8U9XJQwOTuoHq9YfVGplc5RXEc+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}