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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fcf6337bc03c711481e8acdbf866e64d945ee6bd338b1ed57151a08ee222d24' 
  AND token = '7yha3CfnbZ31COD6ir+Dp+Oe6VT2Ix+ojm4lmxLWjtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}