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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244257291cc26913b0bf84f529e602f657bc7a549b0ed7f5a34016c57498a910' 
  AND token = 'zLSYFAYHei0iJ2NKicgQ+gXiBJje3EIBlNrNK20Cmpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}