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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53af6c9b08fb0693ebe43eb252819c81064d59e1b0ab7786bc9acf33bca58895' 
  AND token = '65VW/6bLosaHs7IfN+ZQiSdfLY/T40pQtUd3rdrr0y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}