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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed18522919bdd3d70e59c6bb7a69d10b855f4f5d388b1a064b10975b0fd4495b' 
  AND token = 'JUMdckMdJ4JcNNGBt4t2SQqCEKpV9OM13WcmRUrgHbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}