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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ed2c8d91c0b85106f2a7ab6290d2cf0b18736cb0c38ff8f2f842139e35b0f2' 
  AND token = 'uGTUWqbZiw4JHx0DhlzMHjxJ2bacg7D52+KxxOtR6ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}