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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2643425b989a7c1e62aa8dc84a8c1fb372b47e58ca7aea7fca47525aefbf8a28' 
  AND token = 'N/cd073yBgPDeYVnOJRsNWh9FdZlm/+XKNb7y6SyFdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}