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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba65e2e00cb2d5f5453c3fee4ee405c2951acc412b616e7f36ada21658c66aa' 
  AND token = 'hDumw83D0ku/I63f4kmPV/lYISi9LGrRnMqafckQa48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}