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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b080eb8fa0179397c82fa5c929956ef6fa0dbddc42d48dbdd317db0c6882b01f' 
  AND token = 'EwQCLZ9Lrd+/OWOf/btTB24AMuFMmjt1f0dyfKc+Xxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}