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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f752f9c91aafb0ec0b6bbe3d2454181d3e9f098202468390069d99e9c51baf' 
  AND token = 'TFC81h3Fej8OIBoiWl+KENmF6fLY3VZsRgo1PIc/XO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}