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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49180ac2f8e6a9308768724a00a97c94b3378ea55b55e67924102df5027f39c' 
  AND token = '15rOTjoHpkgI8ZcEf2UgdxDK2mZnM/BZ5izgZ83g5qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}