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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2932f3dff1353e25a080ed6da52bb55ab800ff647c3aabe4ae8d628685387c2' 
  AND token = '6uYZ2vlJXn8tK0RPh9K3UjZfwnFc6pB8f9KNS7Xc02I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}